Anti-RNLS Antibody

Rs. 68,577.00
SKU stj70700

General Information

Product name Anti-RNLS Antibody
Short Description Goat polyclonal to RNLS
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-RNLS Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 37.8 kDa
Database Links
Alternative Names RNLSRenalase RNLS antibodyC10orf59
Function Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+), The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure, Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk, High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis,
Cellular Localization Secreted
Tissue Specificity Secreted into the blood by the kidney, highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine, its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects,
Swiss-Prot Key

 

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