Anti-ROS1 Antibody

Rs. 57,098.00
SKU stj72808

General Information

Product name Anti-ROS1 Antibody
Short Description Goat polyclonal to ROS1
Description
Applications ELISA
Dilution range
Protein Name Anti-ROS1 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 263.9 kDa
Database Links
Alternative Names ROS1Proto-oncogene tyrosine-protein kinase ROS ROS1 antibodyMCF3 antibodyROS
Function Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium, May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway, Mediates the phosphorylation of PTPN11, an activator of this pathway, May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth, Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology, May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2,
Cellular Localization Cell membrane
Tissue Specificity Expressed in brain, expression is increased in primary gliomas,
Swiss-Prot Key

 

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