Anti-SCNN1G Antibody

Rs. 45,619.00
SKU stj27879

General Information

Product name Anti-SCNN1G Antibody
Short Description Rabbit polyclonal to SCNN1G
Description Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:100
Protein Name Anti-SCNN1G Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 85-355 of human SCNN1G (NP_001030.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 74.3 kDa
Database Links
Alternative Names SCNN1GAmiloride-sensitive sodium channel subunit gamma antibodyEpithelial Na(+ antibodychannel subunit gamma antibodyENaCG antibodyGamma-ENaC antibodyGamma-NaCH antibodyNonvoltage-gated sodium channel 1 subunit gamma antibodySCNEGSCNN1G
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride, Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells, Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus, Controls the reabsorption of sodium in kidney, colon, lung and sweat glands, Also plays a role in taste perception.
Cellular Localization Apical cell membrane
Tissue Specificity Expressed in kidney (at protein level).
Swiss-Prot Key

 

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