Anti-SEPT7 Antibody

Rs. 45,619.00
SKU stj28963

General Information

Product name Anti-SEPT7 Antibody
Short Description Rabbit polyclonal to SEPT7
Description This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Protein Name Anti-SEPT7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 307-436 of human SEPT7 (NP_001011553.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 50.7 kDa
Database Links
Alternative Names SEPT7Septin-7 antibodyCDC10 protein homologSEPT7 antibodyCDC10
Function Filament-forming cytoskeletal GTPase, Required for normal organization of the actin cytoskeleton, Required for normal progress through mitosis, Involved in cytokinesis, Required for normal association of CENPE with the kinetochore, Plays a role in ciliogenesis and collective cell movements, Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Cellular Localization Cytoplasm.
Tissue Specificity Widely expressed.
Swiss-Prot Key

 

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