Anti-SERPINB1 Antibody

Rs. 45,619.00
SKU stj28013

General Information

Product name Anti-SERPINB1 Antibody
Short Description Rabbit polyclonal to SERPINB1
Description The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:20 - 1:100
Protein Name Anti-SERPINB1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 100-379 of human SERPINB1 (NP_109591.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 42.7 kDa
Database Links
Alternative Names SERPINB1Leukocyte elastase inhibitor antibodyLEI antibodyMonocyte/neutrophil elastase inhibitor antibodyEI antibodyM/NEI antibodyPeptidase inhibitor 2 antibodyPI-2 antibodySerpin B1SERPINB1 antibodyELANH2 antibodyMNEI antibodyPI2
Function Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3, Also functions as a potent intracellular inhibitor of granzyme H.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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