Anti-SESN2 Antibody

Rs. 45,619.00
SKU stj29651

General Information

Product name Anti-SESN2 Antibody
Short Description Rabbit polyclonal to SESN2
Description This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-SESN2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 211-480 of human SESN2 (NP_113647.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 54.5 kDa
Database Links
Alternative Names SESN2Sestrin-2 SESN2 antibodyHi95 antibodySEST2
Function Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex, In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling.
Cellular Localization Cytoplasm
Tissue Specificity Widely expressed.
Swiss-Prot Key

 

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