Anti-SESN3 Antibody

Rs. 45,619.00
SKU stj27143

General Information

Product name Anti-SESN3 Antibody
Short Description Rabbit polyclonal to SESN3
Description This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Anti-SESN3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.3 kDa
Database Links
Alternative Names SESN3Sestrin-3SESN3 antibodySEST3
Function May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway.
Cellular Localization Cytoplasm
Tissue Specificity Widely expressed.
Swiss-Prot Key

 

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