Anti-SF3A3 Antibody

Rs. 45,619.00
SKU stj25497

General Information

Product name Anti-SF3A3 Antibody
Short Description Rabbit polyclonal to SF3A3
Description This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Anti-SF3A3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 292-501 of human SF3A3 (NP_006793.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 58.8 kDa
Database Links
Alternative Names SF3A3Splicing factor 3A subunit 3 antibodySF3a60 antibodySpliceosome-associated protein 61 antibodySAP 61SF3A3 antibodySAP61
Function Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA, Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA, May also be involved in the assembly of the 'E' complex
Cellular Localization Nucleus speckle
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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