Anti-SFTPC Antibody

Rs. 45,619.00
SKU stj25509

General Information

Product name Anti-SFTPC Antibody
Short Description Rabbit polyclonal to SFTPC
Description This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-SFTPC Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SFTPC (NP_001165881.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 21.1 kDa
Database Links
Alternative Names SFTPCPulmonary surfactant-associated protein C antibodySP-C antibodyPulmonary surfactant-associated proteolipid SPL(Val antibody antibodySP5SFTPC antibodySFTP2
Function Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces
Cellular Localization Secreted, extracellular space, surface film
Tissue Specificity
Swiss-Prot Key

 

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