Anti-SHBG Antibody

Rs. 45,619.00
SKU stj29586

General Information

Product name Anti-SHBG Antibody
Short Description Rabbit polyclonal to SHBG
Description This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:100 - 1:200
Protein Name Anti-SHBG Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-170 of human SHBG (NP_001031.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.8 kDa
Database Links
Alternative Names SHBGSex hormone-binding globulin antibodySHBG antibodySex steroid-binding protein antibodySBP antibodyTestis-specific androgen-binding protein antibodyABP antibodyTestosterone-estradiol-binding globulin antibodyTeBG antibodyTestosterone-estrogen-binding globulinSHBG
Function Functions as an androgen transport protein, but may also be involved in receptor mediated processes, Each dimer binds one molecule of steroid, Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol, Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration
Cellular Localization Secreted
Tissue Specificity Isoform 1 and isoform 2 are present in liver and testis
Swiss-Prot Key

 

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