Anti-SIRT3 Antibody

Rs. 45,619.00
SKU stj27372

General Information

Product name Anti-SIRT3 Antibody
Short Description Rabbit polyclonal to SIRT3
Description This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:100 - 1:200
Protein Name Anti-SIRT3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human SIRT3 (NP_036371.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.6 kDa
Database Links
Alternative Names SIRT3NAD-dependent protein deacetylase sirtuin-3 antibodymitochondrial antibodyhSIRT3SIRT3 antibodySIR2L3
Function NAD-dependent protein deacetylase.
Cellular Localization Mitochondrion matrix
Tissue Specificity Widely expressed.
Swiss-Prot Key

 

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