Anti-SLC4A8 Antibody

Rs. 57,098.00
SKU stj72197

General Information

Product name Anti-SLC4A8 Antibody
Short Description Goat polyclonal to SLC4A8
Description
Applications ELISA
Dilution range
Protein Name Anti-SLC4A8 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 122.9 kDa
Database Links
Alternative Names SLC4A8Electroneutral sodium bicarbonate exchanger 1 antibodyElectroneutral Na(+ antibody-driven Cl-HCO3 exchanger antibodySolute carrier family 4 member 8 antibodyk-NBC3SLC4A8 antibodyKIAA0739 antibodyNBC antibodyNBC3 antibodyNDCBE1
Function Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1, Plays a major role in pH regulation in neurons, May be involved in cell pH regulation by transporting HCO3(-) from blood to cell, Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells, Also mediates lithium-dependent HCO3(-) cotransport, May be regulated by osmolarity,
Cellular Localization Membrane
Tissue Specificity Expressed in the pyramidal cells of the hippocampus (at protein level), highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney, low expression levels observed in pancreas and kidney cortex,
Swiss-Prot Key

 

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