Anti-SPRY2 Antibody

Rs. 61,689.00
SKU stj28184

General Information

Product name Anti-SPRY2 Antibody
Short Description Rabbit polyclonal to SPRY2
Description This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Anti-SPRY2 Antibody
Immunogen A synthetic peptide of human SPRY2
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 34.7 kDa
Database Links
Alternative Names SPRY2Protein sprouty homolog 2 antibodySpry-2SPRY2
Function May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity
Swiss-Prot Key

 

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