Anti-SPTBN1 Antibody

Rs. 45,619.00
SKU stj25683

General Information

Product name Anti-SPTBN1 Antibody
Short Description Rabbit polyclonal to SPTBN1
Description Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:1000 - 1:3000
Protein Name Anti-SPTBN1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 2100-2200 of human SPTBN1 (NP_003119.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 274.6 kDa
Database Links
Alternative Names SPTBN1Spectrin beta chain antibodynon-erythrocytic 1 antibodyBeta-II spectrin antibodyFodrin beta chain antibodySpectrin antibodynon-erythroid beta chain 1SPTBN1 antibodySPTB2
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane
Cellular Localization Cytoplasm, cytoskeleton
Tissue Specificity Isoform 2 is present in brain, lung and kidney (at protein level).
Swiss-Prot Key

 

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