Anti-SRSF7 Antibody

Rs. 61,689.00
SKU stj27863

General Information

Product name Anti-SRSF7 Antibody
Short Description Rabbit polyclonal to SRSF7
Description The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:200
Protein Name Anti-SRSF7 Antibody
Immunogen A synthetic peptide of human SFRS7
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 27.4 kDa
Database Links
Alternative Names SRSF7Serine/arginine-rich splicing factor 7 antibodySplicing factor 9G8 antibodySplicing factor antibodyarginine/serine-rich 7SRSF7 antibodySFRS7
Function Required for pre-mRNA splicing, Can also modulate alternative splicing in vitro, Represses the splicing of MAPT/Tau exon 10, May function as export adapter involved in mRNA nuclear export such as of histone H2A, Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway)
Cellular Localization Nucleus
Tissue Specificity Brain, liver, kidney and lung
Swiss-Prot Key

 

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