Anti-SSTR5 Antibody

Rs. 45,619.00
SKU stj25708

General Information

Product name Anti-SSTR5 Antibody
Short Description Rabbit polyclonal to SSTR5
Description Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-SSTR5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 275-364 of human SSTR5 (NP_001044.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 39.2 kDa
Database Links
Alternative Names SSTR5Somatostatin receptor type 5 antibodySS-5-R antibodySS5-R antibodySS5RSSTR5
Function Receptor for somatostatin 28 and to a lesser extent for somatostatin-14, The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, Increases cell growth inhibition activity of SSTR2 following heterodimerization.
Cellular Localization Cell membrane
Tissue Specificity Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus, no expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.
Swiss-Prot Key

 

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