Anti-STAT4 Antibody

Rs. 45,619.00
SKU stj29071

General Information

Product name Anti-STAT4 Antibody
Short Description Rabbit polyclonal to STAT4
Description The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Protein Name Anti-STAT4 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 569-748 of human STAT4 (NP_003142.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 85.9 kDa
Database Links
Alternative Names STAT4Signal transducer and activator of transcription 4STAT4
Function Carries out a dual function: signal transduction and activation of transcription, Involved in IL12 signaling
Cellular Localization Cytoplasm, Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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