Anti-STEAP4 Antibody

Rs. 45,619.00
SKU stj25730

General Information

Product name Anti-STEAP4 Antibody
Short Description Rabbit polyclonal to STEAP4
Description The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-STEAP4 Antibody
Immunogen A synthetic peptide of human STEAP4
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 52 kDa
Database Links
Alternative Names STEAP4Metalloreductase STEAP4 STEAP4 antibodySTAMP2 antibodyTNFAIP9
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+) (By similarity), Uses NADP(+) as acceptor (By similarity), Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity), Associated with obesity and insulin-resistance.
Cellular Localization Cell membrane
Tissue Specificity Ubiquitous, highly expressed in adipose tissue, expressed in placenta, lung, heart and prostate, detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine, highly expressed in joints of patients with rheumatoid arthritis and localized with cd68 cells, a marker for macrophages.
Swiss-Prot Key

 

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