Anti-SUZ12 Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110096

General Information

Product name Anti-SUZ12 Antibody
Short Description Rabbit polyclonal to SUZ12
Description This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
Applications WB,IHC,IP
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:100
Protein Name Polycomb protein SUZ12Chromatin precipitated E2F target 9 proteinChET 9 proteinJoined to JAZF1 proteinSuppressor of zeste 12 protein homolog
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 470-739 of human SUZ12 (NP_056170.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 83.1 kDa
Database Links
Alternative Names SUZ12Polycomb protein SUZ12 antibodyChromatin precipitated E2F target 9 protein antibodyChET 9 protein antibodyJoined to JAZF1 protein antibodySuppressor of zeste 12 protein homologSUZ12 antibodyCHET9 antibodyJJAZ1 antibodyKIAA0160
Function Polycomb group (PcG) protein, Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene, The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems, Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Cellular Localization Nucleus
Tissue Specificity Overexpressed in breast and colon cancer.
Swiss-Prot Key

 

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