Anti-TERT Antibody

Rs. 68,577.00
SKU stj72725

General Information

Product name Anti-TERT Antibody
Short Description Goat polyclonal to TERT
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-TERT Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 127 kDa
Database Links
Alternative Names TERTTelomerase reverse transcriptase TERT antibodyEST2 antibodyTCS1 antibodyTRT
Function Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes, Active in progenitor and cancer cells, Inactive, or very low activity, in normal somatic cells, Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme, Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3', The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension, More active on substrates containing 2 or 3 telomeric repeats, Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers, Modulates Wnt signaling, Plays important roles in aging and antiapoptosis,
Cellular Localization Nucleus, nucleolus, Nucleus, nucleoplasm, Nucleus, Chromosome, telomere, Cytoplasm, Nucleus, PML body,
Tissue Specificity Expressed at a high level in thymocyte subpopulations, at an intermediate level in tonsil t-lymphocytes, and at a low to undetectable level in peripheral blood t-lymphocytes,
Swiss-Prot Key

 

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