Anti-TLN1 Antibody

Rs. 45,619.00
SKU stj25860

General Information

Product name Anti-TLN1 Antibody
Short Description Rabbit polyclonal to TLN1
Description This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-TLN1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TLN1 (NP_006280.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 269.8 kDa
Database Links
Alternative Names TLN1Talin-1TLN1 antibodyKIAA1027 antibodyTLN
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane, High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).
Cellular Localization Cell projection, ruffle membrane.
Tissue Specificity
Swiss-Prot Key

 

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