Anti-TMED10 Antibody

Rs. 45,619.00
SKU stj28854

General Information

Product name Anti-TMED10 Antibody
Short Description Rabbit polyclonal to TMED10
Description This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-TMED10 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 35-190 of human TMED10 (NP_006818.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 25 kDa
Database Links
Alternative Names TMED10Transmembrane emp24 domain-containing protein 10 antibody21 kDa transmembrane-trafficking protein antibodyS31III125 antibodyS31I125 antibodyTmp-21-I antibodyTransmembrane protein Tmp21 antibodyp23 antibodyp24 family protein delta-1 antibodyp24delta1 antibodyp24deltaTMED10 antibodyTMP21
Function Involved in vesicular protein trafficking, Mainly functions in the early secretory pathway, Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side, In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor
Cellular Localization Golgi apparatus, cis-Golgi network membrane
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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