Anti-TNFRSF10B Antibody

Rs. 45,619.00
SKU stj25885

General Information

Product name Anti-TNFRSF10B Antibody
Short Description Rabbit polyclonal to TNFRSF10B
Description The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-TNFRSF10B Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 56-210 of human TNFRSF10B (NP_003833.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47.9 kDa
Database Links
Alternative Names TNFRSF10BTumor necrosis factor receptor superfamily member 10B antibodyDeath receptor 5 antibodyTNF-related apoptosis-inducing ligand receptor 2 antibodyTRAIL receptor 2 antibodyTRAIL-R2 antibodyCD antigen CD262TNFRSF10B antibodyDR5 antibodyKILLER antibodyTRAILR2 antibodyTRICK2 antibodyZTNFR9 antibodyUNQ160/PRO186
Function Receptor for the cytotoxic ligand TNFSF10/TRAIL mediating apoptosis, Promotes the activation of NF-kappa-B, Essential for ER stress-induced apoptosis.
Cellular Localization Membrane
Tissue Specificity Widely expressed in adult and fetal tissues
Swiss-Prot Key

 

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