Anti-TNFRSF13B Antibody

Rs. 45,619.00
SKU stj27625

General Information

Product name Anti-TNFRSF13B Antibody
Short Description Rabbit polyclonal to TNFRSF13B
Description The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-TNFRSF13B Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 184-293 of human TNFRSF13B (NP_036584.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 31.8 kDa
Database Links
Alternative Names TNFRSF13BTumor necrosis factor receptor superfamily member 13B antibodyTransmembrane activator and CAML interactor antibodyCD antigen CD267TNFRSF13B antibodyTACI
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity, Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1, Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Cellular Localization Membrane
Tissue Specificity Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes, expressed in resting b-cells and activated t-cells, but not in resting t-cells
Swiss-Prot Key

 

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