Anti-TPP1 Antibody

Rs. 61,689.00
SKU stj28191

General Information

Product name Anti-TPP1 Antibody
Short Description Rabbit polyclonal to TPP1
Description This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-TPP1 Antibody
Immunogen A synthetic peptide of human TPP1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 61.2 kDa
Database Links
Alternative Names TPP1Tripeptidyl-peptidase 1 antibodyTPP-1TPP1 antibodyCLN2 antibodyGIG1 antibodyUNQ267/PRO304
Function Lysosomal serine protease with tripeptidyl-peptidase I activity, May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases, Requires substrates with an unsubstituted N-terminus (By similarity).
Cellular Localization Lysosome
Tissue Specificity Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues
Swiss-Prot Key

 

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