Anti-TRAF3IP2 Antibody

Rs. 45,619.00
SKU stj28859

General Information

Product name Anti-TRAF3IP2 Antibody
Short Description Rabbit polyclonal to TRAF3IP2
Description This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-TRAF3IP2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRAF3IP2 (NP_679211.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 64.7 kDa
Database Links
Alternative Names TRAF3IP2Adapter protein CIKS antibodyConnection to IKK and SAPK/JNK antibodyNuclear factor NF-kappa-B activator 1 antibodyACT1 antibodyTRAF3-interacting protein 2TRAF3IP2 antibodyC6orf2 antibodyC6orf4 antibodyC6orf5 antibodyC6orf6
Function Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK
Cellular Localization
Tissue Specificity Widely expressed
Swiss-Prot Key

 

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