Anti-TRIM72 Antibody

Rs. 68,577.00
SKU stj72398

General Information

Product name Anti-TRIM72 Antibody
Short Description Goat polyclonal to TRIM72
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-TRIM72 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 52.7 kDa
Database Links
Alternative Names TRIM72Tripartite motif-containing protein 72 antibodyMitsugumin-53 antibodyMg53TRIM72 antibodyMG53
Function Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites, Specifically binds phosphatidylserine, Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site, This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation, Probably acts upstream of the Ca(2+)-dependent membrane resealing process, Required for transport of DYSF to sites of cell injury during repair patch formation, Regulates membrane budding and exocytosis, May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity),
Cellular Localization Cell membrane, sarcolemma
Tissue Specificity
Swiss-Prot Key

 

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