Anti-TRPV6 Antibody

Rs. 61,689.00
SKU stj25977

General Information

Product name Anti-TRPV6 Antibody
Short Description Rabbit polyclonal to TRPV6
Description This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-TRPV6 Antibody
Immunogen A synthetic peptide of human TRPV6
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 87.3 kDa
Database Links
Alternative Names TRPV6Transient receptor potential cation channel subfamily V member 6 antibodyTrpV6 antibodyCaT-like antibodyCaT-L antibodyCalcium transport protein 1 antibodyCaT1 antibodyEpithelial calcium channel 2TRPV6 antibodyECAC2
Function Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine in a voltage-independent manner, Heteromeric assembly with TRPV5 seems to modify channel properties, TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Cellular Localization Cell membrane
Tissue Specificity Expressed at high levels in the gastrointestinal tract, including esophagus, stomach, duodenum, jejunum, ileum and colon, and in pancreas, placenta, prostate and salivary gland, expressed at moderate levels in liver, kidney and testis, expressed in trophoblasts of placenta villus trees (at protein level), expressed in locally advanced prostate cancer, metastatic and androgen-insensitive prostatic lesions but not detected in healthy prostate tissue and benign prostatic hyperplasia.
Swiss-Prot Key

 

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