Anti-USP19 Antibody

Rs. 57,098.00
SKU stj71618

General Information

Product name Anti-USP19 Antibody
Short Description Goat polyclonal to USP19
Description
Applications ELISA
Dilution range
Protein Name Anti-USP19 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 145.7 kDa
Database Links
Alternative Names USP19Ubiquitin carboxyl-terminal hydrolase 19 USP19 antibodyKIAA0891 antibodyZMYND9
Function Deubiquitinating enzyme that regulates the degradation of various proteins, Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation, Involved in decreased protein synthesis in atrophying skeletal muscle, Modulates transcription of major myofibrillar proteins, Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates, Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination, Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner, Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis, Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis, Exhibits a preference towards 'Lys-63'-linked ubiquitin chains,
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity
Swiss-Prot Key

 

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