Anti-ZNRF1 Antibody

Rs. 68,577.00
SKU stj72828

General Information

Product name Anti-ZNRF1 Antibody
Short Description Goat polyclonal to ZNRF1 (mouse)
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-ZNRF1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 23.8 kDa
Database Links
Alternative Names Anti-ZNRF1 (mouse) Antibody
Function E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation, Plays a role in the establishment and maintenance of neuronal transmission and plasticity, Regulates Schwann cells differentiation by mediating ubiquitination of GLUL, Promotes Wallerian degeneration, a neurodegeneration disorder, by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons,
Cellular Localization Endosome, Lysosome, Membrane
Tissue Specificity
Swiss-Prot Key

 

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