ANXA2R Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16270

Overview

Synonyms Annexin 2 receptor,Annexin II receptor,Annexin-2 receptor,ANXA2R,AX2R,AX2R,AXIIR,C5orf39,Chromosome 5 open reading frame 39
Swissprot Q3ZCQ2
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human ANXA2R
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.7mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background ANXA2R (annexin-2 receptor), also known as AX2R or C5orf39, is a 193 amino acid protein that is widely expressed and may act as an annexin II receptor on marrow stromal cells to induce osteoclast formation. In addition, ANXA2R is highly expressed in lymphocytes and is also found in resting CD4+ and CD8+ T cells. The gene encoding ANXA2R maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene.

 

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