APBA2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16163

Overview

Synonyms Adapter protein X11beta,Amyloid beta A4 precursor protein-binding family A member 2,APBA2,APBA2,D15S1518E,HsT16821,LIN 10,MGC:14091,MGC99508,Mint 2,Mint-2,MINT2,Neuron-specific X11L protein,Neuronal Munc18-1-interacting protein 2,Phosphotyrosine binding/interacting domain (PTB) bearing protein,X11 beta,X11 like protein,X11l
Swissprot Q99767
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human APBA2
Application IHC,ELISA
Recommended dilution IHC 1:100-1:300
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. 

 

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