APOC3 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-33627

Overview

Synonyms APOC3,APO C3,Apo CIII,Apo-CIII,APOC 3,ApoC III,ApoC-III,APOC3,APOC3,ApoCIII,Apolipoprotein C III,Apolipoprotein C-III,Apolipoprotein C3,ApolipoproteinCIII,MGC150353
Swissprot P02656
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the C-terminal region of human ApoC-III.
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.APOC3 (Apolipoprotein C3) is a Protein Coding gene. Diseases associated with APOC3 include Apolipoprotein C-Iii Deficiency and Hyperalphalipoproteinemia. Among its related pathways are Metabolism of fat-soluble vitamins and Statin Pathway. GO annotations related to this gene include lipid binding and cholesterol binding.

 

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