ARHGEF6 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16170

Overview

Synonyms Alpha Pix,Alpha-Pix,ARHG6,ARHGEF6,COOL 2,COOL-2,COOL2,Mental retardation,X linked 46,MRX46,PAK interacting exchange factor alpha,PAK-interacting exchange factor alpha,PIXA,Rac/Cdc42 guanine exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor 6,Rho guanine nucleotide exchange factor 6
Swissprot Q15052
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human ARHGEF6
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.7mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.

 

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