ATP7A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16268

Overview

Synonyms ATP 7A,ATP7A,ATP7A,ATPase copper transporting alpha polypeptide,ATPase Cu++ transporting alpha polypeptide (Menkes syndrome),ATPase Cu++ transporting alpha polypeptide,Copper pump 1,Copper transporting ATPase 1,Copper-transporting ATPase 1,Cu++ transporting P type ATPase,DSMAX,FLJ17790,MC 1,MC1,Menkes disease associated protein,Menkes disease-associated protein,Menkes syndrome,MK,MNK,OHS,OTTHUMP00000062077,SMAX3
Swissprot Q04656
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide of human ATP7A
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.

 

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