AUP1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-14564

Overview

Synonyms AA589454,Ancient ubiquitous protein 1,AUP 1,aup1,AUP1
Swissprot Q9Y679
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human AUP1
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.5mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

 

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