C3 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64531

Overview

Synonyms Acylation-stimulating protein cleavage product,AHUS5,ARMD9,ASP,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1,C3,CO3,Complement C3,Complement C3 beta chain,Complement C3c alpha' chain fragment 2,Complement component 3,Complement component C3,Complement factor 3,CPAMD1,Plp
Swissprot P01024
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human C3
Application WB,IHC
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage buffer
Background Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

 

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