CBX8 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-13978

Overview

Synonyms Cbx8,CBX8,Chromobox Homolog 8 (Drosophila Pc Class),Chromobox Homolog 8 (Pc Class Homolog,Drosophila),Chromobox Homolog 8,Chromobox protein homolog 8,hPc3,Pc Class 3 Homolog (Drosophila),Pc Class 3 Homolog,Pc3,Polycomb 3,Polycomb 3 homolog,RC1,Rectachrome 1
Swissprot Q9HC52
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human CBX8
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:10-1:50
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

 

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