CCRL2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30799

Overview

Synonyms C-C chemokine receptor-like 2,CCRL2,CCRL2,Chemokine (C-C motif) receptor like 2,Chemokine receptor CCR11,Chemokine receptor X,CKRX,CRAM A,CRAM B,CRAMA,CRAMB,FLJ55815,HCR,MGC116710,MGC34104,Putative MCP 1 chemokine receptor,Putative MCP-1 chemokine receptor
Swissprot O00421
Source Rabbit
Reactivity Human
Immunogen Synthesized peptide derived from the Internal region of human CCRL2
Application WB,IF,ELISA
Recommended dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.CCRL2 (C-C Motif Chemokine Receptor Like 2) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor binding. An important paralog of this gene is CCR3.

 

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