CD11b Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-34231

Overview

Synonyms antigen CD11b (p170),Antigen CD11b p170,CD11 antigen like family member B,CD11 antigen-like family member B,CD11b,CD11b/CD18,CD49d,Cell surface glycoprotein MAC-1 subunit alpha,Complement component 3 receptor 3 subunit,Complement Component Receptor 3 Alpha,Complement receptor type 3,alpha subunit,CR 3 alpha chain (CR3A),CR 3 alpha chain,CR-3 alpha chain,CR3,CR3A,F730045J24Rik,Integrin Alpha M,Integrin alpha M chain,Integrin alpha-M,Integrin beta 2 alpha subunit,Integrin subunit alpha M,integrin,alpha M (complement component 3 receptor 3 subunit),ITAM,ITGAM,Leukocyte adhesion receptor MO1,Ly-40,MAC 1,Mac-1a,MAC1,Mac1,alpha subunit,MAC1A,Macrophage antigen alpha polypeptide,MGC117044,Mo1,alpha subunit,MO1A,Neutrophil adherence receptor alpha M subunit,Neutrophil adherence receptor,SLEB6
Swissprot P11215
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthesized peptide derived from the Internal region of human CD11b.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

 

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