CD180 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-33706

Overview

Synonyms CD180,CD180 antigen,CD180,F630107B15,LY64,Ly78,Lymphocyte antigen 64,lymphocyte antigen 64 radioprotective 105kDa,lymphocyte antigen-64,radioprotective,105kDa,MGC126233,MGC126234,Radioprotective 105 kDa protein,RP105
Swissprot Q99467
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of human CD180.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.CD180 (CD180 Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Activated TLR4 signalling. An important paralog of this gene is TLR4.

 

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