CD34 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-70337

Overview

Synonyms Cd34,CD34 antigen,CD34 molecule,CD34,Cluster designation 34,Hematopoietic progenitor cell antigen CD34,HPCA1,Mucosialin,OTTHUMP00000034733,OTTHUMP00000034734
Swissprot Q64314,P28906
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein corresponding to Mouse CD34
Application WB
Recommended dilution WB 1:500-1:800
Concentration 0.7 mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Background CD34 is a surface glycophosphoprotein expressed on developmentally early lymphohematopoietic stem and progenitor cells with a molecular weight of about 105-120 kD. It is selectively expressed on the majority of hematopoietic stem/progenitor cells,bone marrow stromal cells,capillary endothelial cells,embryonic fibroblasts,and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29,CD44,CD90,CD105 and CD166),negative selection markers (such as CD34 and CD45) are used for MSC identification.

 

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