CD44 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30829

Overview

Synonyms LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44
Swissprot P16070
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from human CD44 around the non-phosphorylation site of Ser706.
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

 

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