CDY1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65368

Overview

Synonyms Chromodomain Y-Linked 1,Chromodomain Protein Y Chromosome 1,EC 2.3.1.48,CDY1A,Testis-Specific Chromodomain Protein On Y,Testis-Specific Chromodomain Protein Y 1,Chromodomain Protein Y-Linked 1,CDY1 CDY1B,CDY
Swissprot Q9Y6F8
Source Rabbit
Reactivity Mouse,Rat
Immunogen Recombinant protein of human CDY1B
Application WB
Recommended dilution WB 1:200 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

 

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