CENPF Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16336


Synonyms AH antigen,Cell cycle dependent 350K nuclear protein,CENF,CENP F,CENP F kinetochore protein,CENP-F,CENPF,CENPF kinetochore protein,CENPF,Centromere protein F 350/400ka,Centromere protein F,Centromere protein F,350/400kDa,CILD31,Hcp 1,Hcp1,Kinetochore protein CENP F,Kinetochore protein CENPF,Mitosin,PRO1779,STROMS
Swissprot P49454
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human CENPF
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.4mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.


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