CES1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60478

Overview

Synonyms ACAT,Acyl coenzyme A cholesterol acyltransferase,Acyl-coenzyme A:cholesterol acyltransferase,Brain carboxylesterase hBr1,Carboxyesterase ES-3,Carboxylesterase ,Carboxylesterase 1 (monocyte/macrophage serine esterase 1),Carboxylesterase 1,Carboxylesterase 1 deficiency, included,Carboxylesterase 2, formerly,CE 1,CEH,Ces-1,CES1,CES2,CESDD1,Cholesterol ester hydrolase, neutral, macrophage-derived,Cholesteryl ester hydrolase,Cocaine carboxylesterase,EC 3.1.1.1,Egasyn,ES-HTEL,ES-x,Es22,EST1,Esterase 22,Esterase,hCE 1,HMSE,HMSE1,Liver carboxylesterase 1,Liver carboxylesterase 3,Methylumbelliferyl acetate deacetylase 1,MGC117365,MGC156521,Monocyte carboxylesterase deficiency, included,Monocyte esterase deficiency, included,Monocyte/macrophage serine esterase,PCE-1,pI 5.5 esterase,Proline-beta-naphthylamidase,REH,Retinyl ester hydrolase,Serine esterase 1,Ses-1,SES1,TGH,Triacylglycerol hydrolase
Swissprot P23141
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human CES1
Application WB,IHC
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

 

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