CHD4 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63554

Overview

Synonyms ATP dependent helicase CHD4,ATP-dependent helicase CHD4,CHD 4,CHD-4,CHD4,CHD4,Chromodomain helicase DNA binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Mi 2 autoantigen 218 kDa protein,Mi 2b,Mi-2 autoantigen 218 kDa protein,Mi2 beta,Mi2-beta
Swissprot Q14839
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human CHD4
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

 

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