CHMP2B Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64620

Overview

Synonyms ALS17,Charged multivesicular body protein 2b,CHM2B,CHMP family, member 2B,CHMP2.5,CHMP2b,Chromatin modifying protein 2b,Chromatin-modifying protein 2b,DMT1,hVps2-2,Vacuolar protein sorting 2, yeast, homolog of, B,Vacuolar protein sorting 2-2,Vacuolar protein sorting-associated protein 2-2,VPS2 homolog B,Vps2-2,VPS2B
Swissprot Q9UQN3
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human CHMP2B
Application WB,IHC,IF
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage buffer
Background This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

 

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