CHSY1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30930

Overview

Synonyms Carbohydrate synthase 1,Chondroitin glucuronyltransferase 1,Chondroitin glucuronyltransferase II,Chondroitin sulfate synthase 1,Chondroitin synthase 1,CHSS1,CHSY,ChSy-1,Chsy1,CSS1,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1,N acetylgalactosaminyltransferase II,N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1,N-acetylgalactosaminyltransferase 1,TPBS
Swissprot Q86X52
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthesized peptide derived from the Internal region of human CHSY1
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. CHSY1 (Chondroitin Sulfate Synthase 1) is a Protein Coding gene. Diseases associated with CHSY1 include Temtamy Preaxial Brachydactyly Syndrome and Brachydactyly. Among its related pathways are Chondroitin sulfate/dermatan sulfate metabolism and Glycosaminoglycan metabolism. GO annotations related to this gene include transferase activity, transferring glycosyl groups and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is CHSY3.

 

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