CK-6A Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10149


Synonyms CK-6A,CK-6D,CK6A,CK6C,CK6D,Cytokeratin-6A,Cytokeratin-6D,K2C6A,K6A,K6C,K6D,keratin 6A,Keratin,Keratin,type II cytoskeletal 6A,Keratin-6A,Krt6a,KRT6C,KRT6D,type II cytoskeletal 6A,Type-II keratin Kb6
Swissprot P02538
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human KRT6A
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.5mg/mL
Clonality Polyclonal


Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.


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